Opening - Junior Specialist in The Denison Lab

Posted: 03.19.2018

The Department of Environmental Toxicology at the University of California, Davis invites applications for a qualified Junior Specialist in support of biochemical and molecular studies related to nuclear receptor mediated mechanisms of gene regulation and the development of recombinant bioassays for toxicant identification and characterization. This individual is expected to utilize biochemical and molecular techniques to investigate the mechanisms underlying ligand- dependent activation the Ah receptor and Ah receptor-dependent gene expression in mammalian cells and will involve the identification and characterization of novel Ah receptor ligands using ligand and DNA binding and gene expression analysis techniques.  The Jr. Specialist will also collaborating with lab personnel in the development and application of AhR- and nuclear hormone receptor-based recombinant cell lines for rapid analysis of biological, environmental and food samples and commercial and consumer products.  They will conduct experiments under the supervision of a senior Research Scientist and the PI, are expected to become familiar with the current state of knowledge in the field by reading background literature, including that suggested by supervisors and relevant independent study. Once trained, this individual is expected to work semi-independently, planning their own work schedule and experiments, with oversight by the Research Scientist and PI.   The ideal candidate will have strong interpersonal, communication, organization and decision-making skills, as well as the ability to work well independently and as part of a team.  They will be expected to participate in the design of the experimental plan and individual experiments, to keep a detailed laboratory notebook including experimental procedures and results and will participate in internal campus seminar series and laboratory research meetings. The Jr. Specialist may be able to participate in and present research results, either short oral presentation or a poster presentation, in local and national meetings. They will be responsible for organizing and summarizing their research results in graphical and/or tabular form for presentations and publications and are expected to participate in the writing of research results for publication. The successful candidate will also assist with the organization and management of day-to-day laboratory operations, including general laboratory maintenance such as cleaning of glassware, putting away glassware and supplies, autoclaving materials, ordering supplies, preparation of solutions and media, maintenance of cell cultures, and maintaining frozen stocks of plasmids and bacteria and ensuring that the lab is a clean and safe place to work.  The successful candidate will be expected to spend a minimum of 5% of their time mentoring and coordinating the activities of undergraduate student researchers working in the Denison lab.  These students typically help with basic lab tasks and complete small research projects closely related to his/her own research.  Not only will the Junior Specialist be expected to assist with their training and discuss experiments with them, but will provide guidance on how to prepare presentations of their work and assist with the writing of these results for publication. In addition, the candidate will participate and contribute to departmental and college seminars, journal clubs and other activities, as applicable.


• Requires Bachelor degree in Biochemistry, Molecular Biology, Environmental Toxicology or a related field with a minimum of one year experience in laboratory research.

• Requires demonstrated experience and expertise in PCR, PCR-based mutagenesis, molecular cloning, plasmid preps, agarose gel electrophoresis, and SDS gels/immunoblotting.


• Preference will be given to applicants with additional demonstrated experience and expertise in

immunoprecipitation and mammalian cell culture techniques including transfection and reporter gene analysis.

SALARY RANGE: Step I, $38,112 Annual

POSITION AVAILABLE/CLOSING DATE: All application materials must be received by

03/25/2018. Applications received after this date will only be considered if the position has not yet been filled.

TERM OF APPOINTMENT: This 100% time position is available for a duration of 12 months with the potential to extend up to an additional 12 months upon satisfactory progress and funding availability.

TO APPLY: To apply, please go to the following link: Applicants should submit a cover letter detailing their specific qualifications for this position and a curriculum vitae that includes the names and contact information for three references. All letters will be treated as confidential per University of California policy and California state law.  Generic cover letters that do not address the specific qualification for this position are not acceptable. Documents/materials must be submitted as PDF files.

QUESTIONS: Please direct questions to Denise Petkus via email to The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified

applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see:

Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UCSC positions funded by federal contracts or sub- contracts require the selected candidate to pass an E-Verify check. More information is available

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